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Weighed down by guilt: Research shows it’s more than a metaphor

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Ever feel the weight of guilt? Lots of people say they do. They’re “carrying guilt” or “weighed down by guilt.” Are these just expressions, or is there something more to these metaphors? Researchers have now found evidence that the emotional experience of guilt can be grounded in subjective bodily sensation.

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Life after Fitbit: Appealing to those who feel guilty vs. free

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Is life better or worse after sticking your Fitbit in a drawer? Researchers surveyed hundreds of people who had abandoned self-tracking tools and found emotions ranged from guilt to indifference to relief that the tracking experience was over.

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Curcumin Improves Memory and Mood

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Daily consumption of a certain form of curcumin — the substance that gives Indian curry its bright color — improved memory and mood in people with mild, age-related memory loss.

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Pediatricians screen more kids for mental health issues if they receive hands-on support

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A new study suggests many more pediatricians would make mental health screenings an integral part of a child’s annual checkup if they received training and support through a proven and powerful method used to improve healthcare processes and outcomes.

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Schizophrenia disrupts the brain’s entire communication system, researchers say

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Some 40 years since CT scans first revealed abnormalities in the brains of schizophrenia patients, international scientists say the disorder is a systemic disruption to the brain’s entire communication system. The study sets the stage for future research on the debilitating mental illness that affects more than 21 million people worldwide. It is the largest analysis of ‘white matter’ differences in a psychiatric disorder to date.

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Even seizure-free, children with epilepsy can face social problems as adults

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Learning difficulties and behavioral problems during childhood can lead to suboptimal social and educational outcomes among young adults with childhood epilepsy even when their seizures are well under control and their disease in remission, according to findings from a study.

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The Mysterious Disappearance of Unipolar Mania

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Mania (link is external) is a mood state characterized by an elevated/euphoric, expansive, or unusually irritable mood lasting for at least one week and that is not the result of substance use. The irritability can also manifest itself as an increased impatience with others, heightened sensitivity to criticism (being “touchy”), or passive-aggressive behaviour (opposition and stubbornness).

 

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Antidepressant Not Working? You Could Be a “Nonresponder”

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Over the years, psychopharmacologists have learned through trial and error that individual patients respond differently to specific antidepressant medications. However, the underlying mechanisms that cause only one out of three patients with depression to benefit from the first type of antidepressant he or she is prescribed have remained enigmatic. Fortunately, this mystery may have just been solved. A pioneering hybrid study on mice and humans recently pinpointed why a specific antidepressant compound successfully alleviates depression in one person but doesn’t work for someone else.

 

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Surrogate decision makers experience psychological distress, study finds

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Nearly half of the 13 million older adults hospitalized annually in the United States are unable to make their own medical decisions and rely on surrogates, usually close family members, to make decisions for them. However little is known about how these surrogates respond to the demands put upon them. A new study explores predictors and frequency of surrogate decision-maker distress and has found high levels of both anxiety and depression.

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Healthy mitochondria could stop Alzheimer’s

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Alzheimer’s disease is the most common form of dementia and neurodegeneration worldwide. A major hallmark of the disease is the accumulation of toxic plaques in the brain, formed by the abnormal aggregation of a protein called beta-amyloid inside neurons. Still without cure, Alzheimer’s poses a significant burden on public health systems. Most treatments focus on reducing the formation of amyloid plaques, but these approaches have been inconclusive. As a result, scientists are now searching for alternative treatment strategies, one of which is to consider Alzheimer’s as a metabolic disease

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