Brazilian Recommendations for Handling of the Current Coverings in the Treatment of the Burned Patient
The purpose of the study was to elaborate nursing actions based on recommendations about the proper management of coverage for the treatment of burn patients.This is a review study. The data collection performed in a virtual environment in the Virtual Health Library (VHL), PubMed and specialized magazines such as BURNS and Brazilian Society of Burns. We used the books and periodicals of the health area, which functioned as a conceptual basis with the following descriptors Mesh / DeSC: Burns; Coverings; Prevention; Nursing. Publications with a trajectory of the last 10 years were used as inclusion criterion. With languages in Spanish, English and Portuguese and articles available in full.
Meningo/myelomeningocele is the most common malformation of medulla spinalis. When people talk for Spina Bifida, often they refer to it as myelomeningocele, which is known as the most serious form. Research objectives Our research is the creation of some statistics for the incidence of children operated with meningo/myelomeningocele, gender, age, place of residence, and the incidence of complicated cases in Hydrocephaly, in the period from April 2010 to April 2014. Hypothesis H1: The incidence of children operated with meningo/myelomeningocele. H2: Complications of meningo/myelomeningocele with Hydrocephaly.
Spasm of the near reflex is characterized by miosis, excessive convergence and accommodative spasm (pseuomyopia) that usually occurs, on a functional basis, in young adults with underlying psychiatric disorders (anxiety, depression, hysteria). When this disorder occurs on a functional basis, miosis is always present as well as variable degrees of convergence and accommodation with pseudomyopia. Accommodative spasm can also occur after a head injury as isolated entity of spasm of the near reflex and causes symptoms (blurred vision, headache, and nausea) that are reversible after cycloplegia. Spasm usually resolves spontaneously after 1-2 years from the head injury, but in some cases may persist for a long time and cycloplegics not provide an effective and definitive solution to the problem. We report a patient with a whiplash-associated accommodative spasm and pseudomyopia, treated with GABA-B receptor agonist (Baclofen) that improved accommodative spasm.
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Long-term Outcome of Laser Photocoagulation Combined with Ranibizumab Intravitreal Injection in Macular Edema Secondary to Retinal Vein Occlusion
To investigate the efficacy of laser photocoagulation combined with ranibizumab intravitreal injection in macular edema secondary to retinal vein occlusion in long term.35 eyes with branch retinal vein occlusion (BRVO) and 37 eyes with central retinal vein occlusion (CRVO) treated with or without laser combined with ranibizumab were investigated in this retrospective study. Laser was conducted 7-10 days after the third ranibizumab injection if fluorescein angiography showed ischemic area. In BRVO, patients may receive both macular grid and local peripheral retinal laser. In CRVO, patients just received peripheral retinal laser. We estimated the changes in visual acuity, central retinal thickness (CRT), number of injections and laser over 14 months.
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University of Sussex scientists have made a telling breakthrough in detailing the formation of ‘flashbulb memories’, which can help a snail find a sugary treat but also mean a war survivor repeatedly relives their trauma. The new research brings us much closer to understanding how traumatic memories could be controlled and the cruel blockade on new memories lifted. Prof George Kemenes and Dr Sergei Korneev at the University of Sussex have identified a specific molecule, a microRNA (miRNA, a very short RNA that does not code any proteins), which plays a key role in ensuring a long-term memory is formed. The finding could be an important step towards developing treatments for dementia patients as it sheds new light into how two ‘yin and yang’ proteins, CREB1 and CREB2, control the formation or suppression of memories. The findings from this BBSRC-funded project are significant because it is the first time that specific miRNAs have been shown to play key roles in the forming of long-term memories after a single episode of learning and adds new understanding to how even simple organisms like snails can remember a task after just one attempt. The discovery, by neuroscientists working in the School of Life Sciences at the University of Sussex and assisted by colleagues at the University of Oxford and in the Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, was established through testing how great pond snails (Lymnaea stagnalis) are able to retain the memory of carrying out a simple task through single trial learning. In tests, levels of the miRNA Lym-miR-137 were found to significantly increase shortly after single trial learning. This then led to a reduction in the protein Lym-CREB2 mRNA, which is known to play a role in the restriction of memories by acting as a molecular constraint of memory formation. The results were initially a surprise to the research team as previous experiments on mice showed that reductions in miRNA had enhanced some types of learning and memory. The team believe that different types of learning are linked with distinct types of miRNA and that a whole complex ‘soup’ of miRNA might be involved in the formation of different types of memory. The levels of 14 different miRNAs were all found to be altered at differing times during the single-trial learning process. Prof Kemenes believes that by learning how to control the levels of CREB2 and its counterpart CREB1, a drug could be developed that would relieve the block on forming new memories in dementia patients. Similarly it has the potential to be used to help repress painful memories within those suffering from post-traumatic stress disorder. Prof Kemenes said: “Controlling the levels of CREB1 and CREB2 helps animals to retain only the memories that are useful for completing a simple task rather than trying to retain a lot of superfluous information. “The way snails form memories for this kind of learning is similar to how they are formed within humans. “The flashbulb formation of a memory that is then retained for a lifetime often involves the creation of a very negative memory such as something particularly traumatic or violent but it can also happen after something much more pleasant like a first kiss. “The more we can learn about the physical process of forming memories, the more hope there is that we could eventually learn ways to counteract conditions where memories are too traumatic or where new memories are being restricted.”
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Preconception renal function predicted preterm birth in pregnant women who underwent prior liver transplantation, according to a recently published study. “Our results show that the number of live births is increasing in parallel to the number of women of reproductive age undergoing LT. Moreover, the live birth rate has also increased significantly over the last three decades,” Tiong Y. Lim, MD, from King’s College Hospital, London, and colleagues wrote. “There are currently limited prognostic markers predicting outcomes in LT recipients wishing to get pregnant. To identify new prognostic markers for maternal and fetal outcomes after liver transplantation, Lim and colleagues conducted a retrospective analysis of all pregnancies in LT recipients presented between 1989 and 2017 at their institution. The study comprised 162 conceptions in 93 women. Median age at transplantation was 24 years (range, 1-41 years) and median age at conception was 30 years (range, 18-47 years). While a small percentage experienced acute cellular rejection, infection, hypertension or graft decompensation during pregnancy, the researchers reported no pregnancy-related maternal death. Of the 162 conceptions, 121 resulted in live birth, 10 were elective terminations of pregnancy, 29 resulted in miscarriage, and two were stillbirths. Median gestation was 36 weeks (range, 4-42 weeks). Higher preconception MELD score correlated with prematurity (8 vs. 7; P = .01) and mycophenolate mofetil exposure correlated with a higher rate for miscarriage (50% vs. 16%; P = .04). Median preconception estimated glomerular filtration rate (eGFR) was lower in patients who had a preterm birth (83 vs. 70 mL/min; P = .02). Preconception eGFR less than 90 mL/min (P = .04) and less than 60 mL/min (P = .004) correlated significantly with preterm delivery. Additionally, median gestation time decreased with each increment in chronic kidney disease stage (P = .003), as 79% of pregnancies in patients with CKD stage 0 or 1 and 69% in patients with CKD stage 2 reached term compared with 33% in patients with CKD stage 3. Multivariate analysis showed that preconception eGFR (OR = 0.98; 95% CI, 0.96-0.99) and gestational hypertension-related complications (OR = 4.34; 95% CI, 1.25-15.23) predicted preterm birth.
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The monitoring and understanding of metabolic and physical responses is critical to determine the sports result. Despite their importance, there are few studies investigating track and field athletes, especially in the school category.
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