Clinical
Apelin and Difference in Cesarean Section and Normal Vaginal Delivery
Abstract Objective: Delivery is an inflammatory process and Apelin, has a vital role in pro-inflammatory process and uterine contractility. Therefore, this article studied maternal serum apelin-36 before and after cesarean (C/S) and natural vaginal delivery (NVD). Material and Methods: In this study, 166 pregnant, 18-40 years old, were studied during weeks 28-32 of pregnancy until after delivery.
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Bone Marrow Cancer Survival
Bone cancer is neoplasm of bone. The survival for bone cancers has improved in recent years because of new and better treatments. For osteosarcomas and Ewing sarcomas that are localized, the five-year survival rate ishigh. If it has spread to distant parts of the body, the five-year survival rate is about 15 to 30 percent. If it has spread only to the lungs, the five-year survival rate in Ewing sarcoma is slightly better than in osteosarcoma.
Branchio-Oto-Renal Syndrome-A Rare Case
Branchio-otorenal syndrome (BOR) is an autosomal dominant syndrome with high penetrance and variable expressivity. Congenital hearing loss, auricular malformations, branchial sinus and renal anomalies are major components. Minor manifestations may be variable. The present case report describes BOR in a 19 year boy whose father is also having same syndrome. Pedigree chart of five generations revealed strong family history. The present case had an uncommon presentation of facial palsy.…….to read more: https://www.scitechnol.com/peer-review/branchiootorenal-syndromea-rare-case-12ia.php?article_id=7472
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Mature Teratomas of the Lesser Omentum
This article describes huge mature teratomas in the lesser omentum, rarely reported in the literatures. Non-enhanced CT scan showed characteristic imaging findings and a correct diagnosis was achieved before operation. Although there are some debates regarding the origin of teratomas in this patient, but operative findings and pathological examination of resected specimen confirms its origin to be from the lesser omentum instead of the pancreas. The CT images will improve our clinical recognition for this rare disease entity. These images are instructive and educative…to read more: https://www.scitechnol.com/peer-review/mature-teratomas-of-the-lesser-omentum-ViHT.php?article_id=7504
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Primary Intramedullary Diffuse Large B cell Lymphoma Mimicking a Spinal Meningioma: A Case Report and Review of the Literature
Non-Hodgkin lymphomas account for only 0.3 to 1.5% of all central nervous neoplasms and are mainly subdivided in B-cell and T-cell lymphomas. Primary spinal involvement of PNCLS is a very rare disease, most being metastatic. We report a rare case of a 62-yearold male with a short history of progressive paraparesis. MRI of the spine showed a homogeneous contrast enhanced tumor mass with dural attachment, assuming a spinal meningioma. During surgery the tumor appeared diffusely grown into the spinal cord without detectable margins. Histological work-up brought up the diagnosis of a diffuse large B-cell-lymphoma (DLBCL). We illustrate the diagnostic steps and pitfalls and highlight the multimodal therapy and oncological features of this rare disease.….to read more: https://www.scitechnol.com/peer-review/does-bladder-cancer-pathology-matter-in-prognosis-and-treatment-qENT.php?article_id=7502
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Juvenile Myelomonocytic Leukemia
Juvenile Myelomonocytic Leukemia (JMML) is a rare childhood cancer that usually occurs in children younger than 2 years old. There are three main types of mutations found in Juvenile myelomonocytic leukemia which occur in a type of white cell known as a monocyte, which are a part of the body’s immune system, Juvenile myelomonocytic leukemia is a serious form of chronic leukaemia. Juvenile myelomonocytic leukemia accounts for less than 1% of all childhood leukaemias diagnosed. Cause of Juvenile myelomonocytic leukemia remains largely unknown. Allogeneic (donor) Stem Cell transplant is the only curative option for children with Juvenile myelomonocytic leukemia.
Read more at https://www.scitechnol.com/journal-of-blood-research-and-hematologic-diseases.php
Cancer Radioimmunotherapy
Radioimmunotherapy (RIT) uses an antibody labelled with a radionuclide to deliver cytotoxic radiation to a target cell. In cancer therapy, an antibody with specificity for a tumor-associated antigen is used to deliver a lethal dose of radiation to the tumor cells. The ability for the antibody to specifically bind to a tumor-associated antigen increases the dose delivered to the tumor cells while decreasing the dose to normal tissues.
Polycythemia vera
Polycythemia vera is a unique blood disorder in which there is an raise in all blood cells, particularly red blood cells. The increase in blood cells makes your blood thicker. This can lead to strokes or tissue and organ damage. Polycythemia vera is caused by a genetic change that develops during your lifetime. It is not an inherited genetic disorder. In most cases it is not known why this happens. There is no cure for polycythemia vera, but proper treatment can help to reduce or delay any problems. Work with your healthcare provider to create a treatment plan that fits your needs. You should also be physically active in order to increase your heart rate and improve your blood flow and also avoid situations in which you could be hurt, and check your feet for any sores.
Oncology Analytics
Oncology analytics provides evidence-based care, utilizes a counseling model within traditional preauthorization management for chemotherapeutic drugs, symptom-management drugs and supporting agents.
The Value of FAK and SLUG Expression in Patients with Breast Carcinoma and Relation of Their Expression to Clinicopathological and Prognostic Parameters
FAK and SLUG positive expression in breast carcinoma was related to positive expression in breast carcinoma was significantly correlated with aggressive molecular subtypes as HER2 amplified and triple negative subtypes, presence of lymph node metastases, high KI67 index, presence of distant metastasis (p<0.001 for all of them), negative ER & PR (p= 0.08), The expression of both markers was significantly positively correlated with each other (p<0.001). FAK and SLUG positive expression in breast carcinoma was associated with shortened recurrence free and overall survival rates (p<0.00)….to read more: https://www.scitechnol.com/peer-review/the-value-of-fak-and-slug-expression-in-patients-with-breast-carcinoma-and-relation-of-their-expression-to-clinicopathological-and-AFwM.php?article_id=7465
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