Artificial Intelligence helps Early Diagnosis of skin cancer

Posted on Updated on

The technology employs machine-learning software to analyze images of skin lesions and provide doctors with objective data on telltale biomarkers of melanoma, which is deadly if detected too late, but highly treatable if caught early.

The AI system — trained using tens of thousands of skin images and their corresponding eumelanin and hemoglobin levels — could initially reduce the number of unnecessary biopsies, a significant health-care cost. It gives doctors objective information on lesion characteristics to help them rule out melanoma before taking more invasive action.

The technology could be available to doctors as early as next year.

E-mail us: dermatology@scitechnol.com

https://www.scitechnol.com/clinical-dermatology-research-journal.php

Advertisements

Skin Complications of Obesity

Posted on Updated on

Obesity is a worldwide public health burden with an increasing prevalence. It is mainly attributed to interactions between diet, sedentary life and genetic predisposition. A chronic accumulation of adipose tissue found in obesity is associated with long-term consequences such as diabetes, cardiovascular diseases, hypercholesterolemia, etc. Many skin changes have been reported in obese patients.

Significantly more skin diseases were found in the obese patient than control; plantar hyperkeratosis, Acanthosis nigricans, Scalp scale (dandruff), Skin tags, Striae cutis, Intertrigo, Callosity, Candida that strongly correlated the degree of obesity. Many patients had more than two conditions. The most frequent combination observed were Acanthosis nigricans with skin tags, Striae and varicosity are significantly more among obese females than obese males.

Obese patients experienced more skin diseases than non-obese. Obese females have more skin diseases than obese males. Obese patients with skin diseases should reduce their weight to improve their skin lesions.

Full article: http://bit.ly/2zcAbHc

E-mail us: dermatology@scitechnol.com

Your Own Blood in Improving Your Look

Posted on Updated on

Aesthetic dermatology is probably the fastest growing branch of the dermato-venereology. New trends in aesthetic medicine underline the natural resources and the use of non-invasive methods in the treatment, replacing the radical invasive methods and the use of medicaments. The benefits of these new procedures are, very short recovery time from the intervention, better tolerance by the patient, low-cost treatment. One of the innovations that is successfully applied in everyday practices at many dermatological and aesthetic departments and clinics is the treatment with plasma rich in platelets (plasma rich platelets). More recently it is being practiced in dermatology for face rejuvenation or so-called vampire lift, and lately in therapy of alopecia and to treat wounds. In fact, the procedure is performed to drawn the blood from the patient, then the blood is centrifuged and leads to the isolation of pure plasma rich in platelets that is rich in growth factors. The procedure can be practiced for more than once without any risk to the patient. New therapeutic modality for rejuvenation combines fractional CO2 laser with PRP (platelet-rich plasma). The combined treatment maximize the deep ablative effect of CO2 laser, as well as underlining the therapeutic effect of platelet-rich plasma. Laser micro-perforations improve plasma rich in platelets penetration. In this era of technological wonders, probably the most surprising things are the natural resources for the treatment of diseases. One of those breathtaking resources is the autologous plasma which demonstrates the inexhaustible possibilities of the human organism. All that is needed is to identify them and explore together with the increasing use of technical means and the hunger for profit of the modern world. However, even in the era of robotics we will remain just people.

E-mail us: dermatology@scitechnol.com

Full Lenght Article: http://bit.ly/2ldjNzJ

 

The Effects of Carbon and Gold Ion Implanted Surfaces on Neuronal Stem Cells’ Functions

Posted on Updated on

Biomaterials have been used in medicine for decades to improve the functions of tissues and organs. They are also used as prosthesis and implants which are designed to substitute functions of a lacking organ or tissue. Carbon (C) and Gold (Au) were particularly chosen due to their biocompatibility and applied as implants for decades. Carbon and gold were great ion sources for medical applications, as well. In this study, polystyrene dishes were modified using gold and carbon ions via ion implantation technique. Using this surface modification method, it was aimed to improve surface characteristics and achieve a bioactive surface for neural stem cells. Even though the integration of stem cells was promising, neural stem cell studies still have many milestones to reach. Neuro-regeneration was the most desired function for people who suffer from neural system diseases. Changing surface characteristics of scaffolds was a way to promote regeneration and ion implantation was one of the methods to modify surface properties which play a huge role in enhancing the proliferation and integration of cells. In this study, it was observed that the ion implantation stimulated the neural proliferation and the implantation of different ions on cell culture surfaces was essential to determine the effects of this technique on adhesion, proliferation, and differentiation and apoptosis properties of cells in details.

https://www.scitechnol.com/biomaterials-medical-applications.php

Chronic Pain, Chronic Opioid Addiction: a Complex Nexus

Posted on Updated on

Over the past two decades, there has been a significant increase in the prescribing of opioids, with associated increases in opioid addiction and overdose deaths. This article reviews the evidence for the effectiveness and risk of developing an opioid use disorder (OUD) in those patients treated with chronic opioid therapy (COT) for chronic non-cancer pain (CNCP). Rates of development of OUD range from 0–50 %, and aberrant drug related behaviors (ADRBs) are reported to be 20 %. Health care providers must properly assess, screen, and carefully monitor patients on COT utilizing evidence-based tools.

https://www.scitechnol.com/journal-medical-toxicology-research.php

Efficacy of a Topical Lotion Containing Lactoferricin, Glycerophosphoinositol Lysine and Verbascoside for External Otitis Due to Atopic Dermatitis

Posted on Updated on

The prevalence of atopic dermatitis (AD) in the general dog population is 3-15% it represents the diagnosis for up to 58% of dogs affected with skin disease. Canine AD has been defined by Halliwell in 2006, as a “genetically predisposed inflammatory and pruritic allergic skin disease with characteristic clinical features, associated with IgE antibodies most commonly directed against environmental allergens”. Indeed, genetic factors and familiar predisposition to the disease have been found to play a major role in its pathogenesis, although the full pathogenesis is still unknown. It is certain that the immunological aberration is usually associated with skin barrier dysfunctions; pro-inflammatory cytokines, neuronal itch stimuli and the animal’s pruritic behaviours establish a vicious cycle of itch that perpetuates and potentially exacerbates the skin lesions and defects in the skin barrier function. The initial clinical feature of canine AD is pruritus, which at the beginning may be associated with no lesion or with primary skin lesions such as erythema and occasionally papules. The mediators that elicit the sensation of pruritus have not been elucidated, but histamine does not appear to be a mediator in dogs in contrast to humans and mice. It is usually a life-long pathology which can be controlled, but it can be seldom cured. The diagnosis of canine AD does not require any analytical test, such as IgE determination and/or intradermal skin test, and it can be done on the basis of pruritus associated with skin lesions. The skin lesions are usually associated with the detachment of corneocytes from live skin. Furthermore, the skin lesions are usually associated with the cytological presence and overgrowth of bacteria (mainly Staphylococcus) and fungal or yeast (mainly Malassezia Pachydermatis) in the damaged region, and it has been purpose that this overgrowth could be also responsible for most of the symptoms. Due to the skin infection, canine AD often develops otitis externa and usually, the signs of atopic otitis were noticed by the owners before the other signs of AD.

E-mail us: dermatology@scitechnol.com

 

2-Octyl Cyanoacrylate Skin Adhesive

Posted on

Surgical adhesives have become more prevalent in the Emergency Department (ED) to close #skin lacerations due to their ease of use, more complete surface contact and microbial barrier properties. They also have unique advantages over traditional suturing in the ED. This includes the ease of closure, the speed of closure, decreased or elimination of the need for topical or injectable anaesthetics, and reducing the need for specific aftercare including suture removal. Prior research has found that liquid skin adhesives for laceration closure are less painful and produce similar cosmetic effects when compared to sutures. While skin adhesives offer advantages opportunities for improvement exist. Ease of application is an important characteristic. The viscosity of the adhesive may cause problems if too low, flowing into sensitive areas including eyes and mucous membranes. If too high it may not adequately cover the wound or create a raised area that patients may find irritating, particularly children who may scratch at these raised areas which can increase the risk of infection.

E-mail us: dermatology@scitechnol.com

Full Article: http://bit.ly/2hnIl3W

L 17 Cytokine in Psoriasis

Posted on

Psoriasis which was considered a disease of abnormal epidermal keratinocyte proliferation later was identified as T helper-1 (Th1) disease because an increase in Th1 pathway cytokines was observed in the lesions and in serum. Currently, a new paradigm has emerged where Th17 cells which produce IL-17 and IL-22, play a central role in the pathogenesis of psoriasis. The differentiation factors (TGF-beta, IL-6, IL-21), the growth and stabilization factor (IL-23), and the intracellular transcription factors (STAT3, RORγt, and RORalpha) are involved in the development of Th17 cells. IL-17A, part of a group of cytokines, called the IL-17 family plays a critical role in the pathogenesis of psoriasis. IL-17A enhances the expression of S100 proteins, chemokines CCL20, CXCL1, CXCL3, CXCL5, CXCL6, and CXCL8, and VEGF in keratinocytes leading to aberrant cell differentiation, proliferation, and immune activation. IL-17A has pleiotropic effects, but its main effect is recruitment and activation of neutrophils, angiogenesis and tissue remodelling by stimulating the production of angiogenic factors and matrix metalloproteases.

E-mail us: dermatology@scitechnol.com

Full article: http://bit.ly/2s0aKDF

Sexually Transmitted Infections among Sex Workers

Posted on Updated on

Sexually transmitted infections (STIs) are a major public health concern in developing countries. They are increasing with the advent of human immunodeficiency virus (HIV) infection, particularly in sub-Saharan Africa. Sex workers (SWs) are the most vulnerable population.

A cross-sectional and prospective survey was conducted at the STIs clinic in Cotonou, from November 2014 to April 2015. The STI clinic is currently the reference centre for the care of SWs and their clients in Cotonou. The SWs and their clients who consulted in the STI clinic for any reason were included with their informed consent. The diagnosis of STI was essentially based on the syndromic approach. Further medical tests were requested when necessary. Retroviral serology was performed free of charge for all included patients. Recruitment was based on a thorough sampling. The data collected with a survey form were analyzed with the Epi Info 7 software, which received the approval of the local ethics committee. Anonymity and confidentiality were respected in the processing of files.

E-mail us: dermatology@scitechnol.com

Get Article: http://bit.ly/2vSjxeC

Get the Best Results From Beauty Products

Posted on

It is certainly not from exotic ingredients or brand-name only products. Obtaining great results depend on having a complete skin care routine. This routine should consist of skin-compatible products, targeted for your desired results. For example, if acne is your main focus, purchase products that combat acne. If lines and wrinkles are bothering you, don’t overload and complicate your product usage. Choose items that target your issues.

It’s actually that simple. Complete skin care means you ‘dot the essential I’s and cross the essential T’s’. And here’s where you start.

  • Cleanse skin to prepare it to absorb corrective actives.
  • Correct skin problems by choosing specific products designed to achieve your results.
  • Hydrate to maintain skin health.
  • Protect from damaging UV rays that lead to wrinkles and uneven skin pigment.

Ensure each step includes quality products. This is the secret to skin care that is repeatedly missed. Don’t be deceived by advertising claims enticing you to the latest and greatest! Learn why complete skin care is important.

While you’re at it, see my advice pages below. They will guide you to creating an effective routine for the results you want!

Read More: https://www.scitechnol.com/clinical-dermatology-research-journal.php

E-mail us: dermatology@scitechnol.com

Necrotic Arachnidism by Zorocrates guerrerensis

Posted on Updated on

The spiders (filo Arthropoda) occupy seventh place in global species richness. The genus Zorocrates Simon, consists of endemic species in Mexico. This arthropod used for feeding or defense, glandular secretions to manipulate their prey (including human), affecting their state of health or causing the death, by what are considered species of medical importance.

We present the case clinical female 19 years old, resident of the Mexico City, who came to the Parasitology Laboratory, National Autonomous University of Mexico (UNAM), commenting that three days before, sitting on his bed, felt pain in the left external tibial region at the level of the third half, discovering a large insect, repelling it immediately; minutes later, there are burning, and erythema in the area of reference, which evolves with formation of vials, which spontaneously bursts. Then presented erythematous, itchy, painful plaques, reason for the requested medical attention. The ulcerative lesion studied with slow progress until the cicatricial process.

Responsible arachnid is presented to the laboratory until the end of the treatment, which is identified as Zorocrates guerrerensis, species located in areas of the Mexico City (bedrooms, bathrooms, patios, zotehuelas, cisterns and gardens). There are no cases reported in Mexico and the world, about accidents caused by this species. It is suggested that the injury is due to the mechanics of the bite and not by the toxic effects of its secretion, which has not yet been characterized and that cannot be ruled out, along with other components, as head of the pathophysiological manifestations.

Read more: http://bit.ly/2lCw3qi

Submit your manuscript: dermatology@scitechnol.com (or) dermatology@scitechnol.org

 

https://scitechnolblog.wordpress.com/2017/02/25/necrotic-arachnidism-by-zorocrates-guerrerensis/

Skin Cancer on the Rise

Posted on Updated on

The researchers report that, between 2000 and 2010, squamous cell carcinoma (also called cutaneous squamous cell carcinoma) diagnoses increased 263 percent, and basal cell carcinomas increased 145 percent. They compared the 2000-2010 period to two other segments of time: 1976-1984 and 1985-1992.

Women 30-49 experienced the greatest increase in basal cell carcinoma diagnoses; whereas, women 40-59 and 70-79 experienced the greatest increase in squamous cell carcinomas.

Men had an increase in squamous cell carcinomas between the first and second time period studied (1976-1984 and 1985-1992), but experienced a slight decline in the 2000-2010 period. However, for basal cell carcinomas, men over 29 showed similar increases in diagnoses in the 2000-2010 period than the two earlier periods.

 

Muscle Movement During Smile

Posted on Updated on

The smile may be the most common and flexible expression, used to reveal some emotions, cover others and manage social interactions that have kept communities secure and organized for millennia. But how do we tell one kind of smile from another?

“When distinguishing among smiles, both scientists and laypeople have tended to focus on true and false smiles. The belief is that if you smile when you’re not happy, the smile is false,” says Paula Niedenthal, a psychology professor at the University of Wisconsin-Madison. “But people smile in many different circumstances and during many emotional states. So asserting that only smiles that result from states of happiness are ‘true’ smiles limits our understanding of this important facial expression.”

Niedenthal and colleagues from Cardiff University and the University of Glasgow published a set of experiments that seek to expand our understanding of the human smile this week in the journal Psychological Science, showing three distinct, reliably recognized expressions — smiles of reward, affiliation and dominance — and describing the facial muscle combinations that make them.

Each smile hinges on an anatomical feature known as the zygomaticus major, straps of facial muscle below the cheekbones that pull up the corners of the mouth. But it’s not the only muscle at work.

Participants in the study looked at thousands of computer-generated expressions with random combinations of facial muscles activated — with one exception.

“We varied everything that could be varied in an expression, but our stimuli included some action from the smile muscle, the zygomaticus,” says Magdalena Rychlowska, a postdoctoral researcher at Cardiff. “We asked participants to tell us when they see a reward or affiliative or a dominance smile, and when the expression is not a smile.”

The researchers turned their participant-sorted smiles back on two more sets of observers, checking recognition and social messages until they had recipes for each smile.

For example, a reward smile — “probably the most intuitive,” Niedenthal says, “the kind of smile you would use with a baby, so he will smile back or do things you like” — is a symmetrical hoist of zygomaticus muscles plus a dash of eyebrow lift and some sharp lip pulling.

Affiliative smiles — used to communicate tolerance, acknowledgement, or a bond, and show that you’re not a threat — come with a similar symmetrical upturn to the mouth, but spread wider and thinner with pressed lips and no exposed teeth.

Dominance smiles are used to signify status and manage social hierarchies. They dispense with the symmetry, pairing a bit of lopsided sneer with the raised brows and lifted cheeks typically associated with expressing enjoyment.

“This facial expression has evolved to solve basic tasks of human living in social groups: Thanks, I like this. Don’t worry, I’m not going to hurt you. Hey, I’m in charge here,” Niedenthal says. “There are so many words people use to describe different smiles, but we see them as describing subtypes of a reward situation or an affiliative situation or a situation of negotiating hierarchy and having disdain for someone else.”

With precise physical descriptions of smile types, researchers can better classify subtypes and study the use and effects of smiles in pivotal human interactions.

“We now know which movements we should look for when we describe smiles from real life,” says Rychlowska. “We can treat smiles as a set of mathematical parameters, create models of people using different types of smiles, and use them in new studies.”

To know more: https://www.scitechnol.com/clinical-dermatology-research-journal.php
Submit your manuscript: dermatology@scitechnol.com (or) dermatology@scitechnol.org

Formation of Melanoma Tumors

Posted on Updated on

Researchers at the University of Iowa did just that, documenting in real time and in 3-D how melanoma cells form tumors. The cells waste no time finding their cancerous cousins, slashing their way through a lab-prepared gel to quickly join other melanoma cells and form tumors.

Biology professor David Soll and his team used unique computer-assisted 3-D reconstruction software to chronicle how both breast tissue cancer cells and melanoma cells form tumors. The group found the two cancers act similarly in the joining stages of tumor formation. With that knowledge, they screened more than four dozen monoclonal antibodies — unique agents that can stop cells from growing or forming tumors and can be mass produced — before finding two that block tumor creation in both types of cancer.

For more related information on the article, visit us on at https://www.scitechnol.com/clinical-dermatology-research-journal.php

Any queries: dermatology@scitechnol.com

Pharmacophore Modeling, 3D-QSAR, and Docking Study

Posted on

Phosphodiesterases 4 enzyme attracts the target for the designing of anti-inflammatory and bronchodilator agents. In many studies pharmacophore and atom based 3D-QSAR studies were carried out for pyrozolo[1,5-a]pyridine/4,4-dimethylpyrazolone analogues.

For more related information on the article, visit us on at http://www.scitechnol.com/pharmaceutics-drug-delivery-research.php

Validation of Stability using the Chromatography Method

Posted on

Many studies were depicted the development of a validated reversed-phase HPLC method for the determination of the primary drug in thepresence of degradation products or pharmaceutical excipients. The separation is carried out on Hypersil BDS C18 column having particle size 5 μ using acetate buffer.

For more related information on the article, visit us on
at https://www.scitechnol.com/peer-review/development-and-validation-of-stability-indicating-hplc-method-for-gefitinib-and-its-related-compounds-and-characterisation-of-deg-XlJY.php?article_id=5776

Get the Best Results From Beauty Products

Posted on

It is certainly not from exotic ingredients or brand-name only products. Obtaining great results depend on having a complete skin care routine. This routine should consist of skin-compatible products, targeted for your desired results. For example, if acne is your main focus, purchase products that combat acne. If lines and wrinkles are bothering you, don’t overload and complicate your product usage. Choose items that target your issues.

It’s actually that simple. Complete skin care means you ‘dot the essential I’s and cross the essential T’s’. And here’s where you start.

  • Cleanse skin to prepare it to absorb corrective actives.
  • Correct skin problems by choosing specific products designed to achieve your results.
  • Hydrate to maintain skin health.
  • Protect from damaging UV rays that lead to wrinkles and uneven skin pigment.

Ensure each step includes quality products. This is the secret to skin care that is repeatedly missed. Don’t be deceived by advertising claims enticing you to the latest and greatest! Learn why complete skin care is important.

While you’re at it, see my advice pages below. They will guide you to creating an effective routine for the results you want!

Know More: https://www.scitechnol.com/clinical-dermatology-research-journal.php

E-mail us: dermatology@scitechnol.com

Radiation dermatitis

Posted on

Irritant contact dermatitis accounts for 80% of all contact dermatitis reactions. It occurs when the skin comes in contact with a substance that acts as an irritant. Even though over 2800 substances have been identified as irritants, almost any substance under the right circumstances can act as an irritant.

Skin Barrier in Irritant Contact Dermatitis
The epidermis acts as a barrier with an outer layer composed of dead cells in a water-protein-lipid matrix.

Acute Irritant Contact Dermatitis
Acute irritant contact dermatitis occurs when the skin comes in contact with a strong toxic chemical such as an acid or alkali. The rash occurs within minutes to hours after exposure and in most cases, healing occurs soon after exposure. This rash usually has sharp borders and consists of redness, vesicles, bullae, or skin sloughing.

  • Picture of irritant contact dermatitis on the foot

Chronic Cumulative Irritant Contact Dermatitis
Chronic cumulative irritant contact dermatitis is the more common of the two. This dermatitis occurs after repeated exposure to low-level irritants, such as soaps or shampoos. The rash may take weeks, months, or even years to develop.

The rash usually has poorly-defined borders, is very itchy, and consists of redness, scaling, fissuring, and lichenification.

  • Picture of irritant contact dermatitis on the hand

Treatment of Irritant Contact Dermatitis
The mainstay of treatment for irritant contact dermatitis is avoiding as many of the irritants as possible.

Other helpful measures include:

  • Reduce water exposure – because frequent water exposure actually dries out the skin and disrupts the barrier function of the epidermis, keep water contact to a minimum.
  • Moisturize – Frequent moisturization improves the barrier function of the skin. Avoid the use of moisturizers with perfumes since these may also act as an irritant.
  • Protection – Because the hands are often affected by irritant contact dermatitis, the use of gloves may help reduce exposure to the irritant.
  • Topical steroids – Medium- to high-strength topical steroids may be needed to reduce inflammation and itching.

To Know more: https://www.scitechnol.com/clinical-dermatology-research-journal.php

Any queries: dermatology@scitechnol.com

Role of Nanoparticles in Targeted Drug Delivery

Posted on

The use of nanotechnology in medicine and more specifically drug delivery is set to spread rapidly. Currently many substances are under investigation for drug delivery and more specifically for cancer therapy.

For more related information on the article, visit us on at http://www.scitechnol.com/pharmaceutics-drug-delivery-research.php

The Significance of Beards

Posted on

Facial hair is in right now, whether it’s a subtle five o’clock shadow, a goatee, a full Duck Dynasty beard or some other variation. But beards haven’t always been this popular, and they’ve represented more than just fashion trends and primitive ways to protect your skin.

Going back to the Dynastic period in Egypt, facial hair was seen as a low class sign of animal tendencies. Men even went as far as removing their eyelashes!

As time went on, beards grew in favor. In ancient Greece, for example, beards were seen as signs of virility, manhood and wisdom. They were cut only during a time of mourning or as a form of punishment to Spartans.

The ancient Romans decided to distinguish themselves from the Greeks by being clean-shaven. It was so important to Roman culture that religious ceremonies were held when boys shaved for the first time.

By the years 330 – 1750 in Europe, facial hair had mixed support. While knights maintained beards as a sign of masculinity and honor, King Henry VIII and Queen Elizabeth weren’t fans, at least on those they ruled. King Henry kept his beard while everyone else had to pay a tax for growing one.

Forward ahead to the early 1900s in America and facial hair was not in vogue. Soldiers in WWI couldn’t have beards because they could interfere with gas masks. This led to a no-beard trend that continued until after WWII. Beards eventually made a comeback years later when they were sported by hippies and the Beatles.

Religions have different views on the topic. Christians didn’t depict Jesus with a beard until 500 CE, and early popes and bishops opposed beards. In Islam, beards are seen as an indicator of religious devotion to the Qur’an. Meanwhile, most Jewish men learn that Leviticus 19:27 maintains they can only trim and remove facial hair with scissors or, in modern times, an electric razor.

Politicians typically avoid beards because historically it was a sign of protest and later it suggested opposition to women’s issues. While many sports clubs used to have a less-than-favorable view of beards, that has changed in recent years. In 2015, more professional baseball players had beards than not.

Today, facial hair is popular enough that there is a World Beard and Mustache Championship and hipster men in New York have been known to pay more than $8,000 for facial hair transplants to fix less-than-perfect beards.

To know more: http://bit.ly/1QM6nmv
Submit your manuscript: dermatology@scitechnol.com (or) dermatology@scitechnol.org

Men With Hair Loss

Posted on

It’s a significant riddle technology has yet to completely solve, but there’s definite progress. Male pattern baldness is that mysterious condition that has enormous social significance but almost no medical significance and it’s been a great boon to the baseball cap industry, of course.

In this survey, we take the pulse of American men who have experienced hair loss, to understand three primary things: how men respond to that hair loss (with treatments or lack thereof), what motivates their responses, and how they feel about the subject overall.

The first order of business for us was to establish how much hair men are losing. Between thinning hair and more significant hair loss that results in bald spots, widow’s peaks and full baldness, it’s a fifty-fifty split. Among the half of men experiencing more severe hair loss, 43 percent report having a bald spot or widow’s peak and seven percent report they are fully bald. Naturally, the response to hair loss is informed by the amount of hair that’s been lost, so it’s important to keep these baselines in mind.

Surprising or not, a majority of men do very little to address their hair loss (particularly in the Northeast)—50 percent have responded by cutting their hair short or shaving it all off, while an additional one in four men don’t do anything different as their hair begins to disappear.

The least likely response is to go under the knife—just one percent of men undergo hair transplant surgery. Much more popular are shampoo treatments and medications like Rogaine and Propecia, the former being a spray, the latter being oral medication.
Guys on the West Coast are by far the most likely to explore over-the-counter treatments—nearly twice as many men experiencing hair loss on the West Coast have tried shampoos, than men in the Northeast. West Coast men are also most likely to have used sprays or medications: 34 percent on the West Coast have tried, versus an average of 18 percent throughout the rest of the country.

What motivates a particular guy’s response to his hair loss? Well, it’s not all about sex appeal. The most common answer was that doing something about it makes men feel more confident (sex appeal aside). That said, one in four men copped to wanting to enhance his sex appeal. Just behind that, statistically, was a desire to “fit in.” And the reasons men were least likely to cite as motivators to do something about their hair loss? It’s important to their work… or their significant other.

To know more: http://bit.ly/1QM6nmv
Submit your manuscript: dermatology@scitechnol.com (or) dermatology@scitechnol.org

Hydrogels Incorporated with Cancer Medicines

Posted on

Electric-field sensitive hydrogels are of great interest for many researchers from the aspects of their usage in several biomaterials applications. Controllable drug release under various voltages offers huge benefits for the controlled drug delivery systems. Electrically sensitive polyvinyl alcohol (PVA) hydrogels loaded with methotrexate (MTX) and other compounds were prepared via a solution casting process, and characterized through various techniques.

To view the full information on the article, visit us on at http://www.scitechnol.com/pharmaceutics-drug-delivery-research.php

Homology Modeling of Versatile Peroxidases from Pleurotus sapidus Reveals Residues for Site Directed Mutagenesis to Enhance the Bioremediation Ability

Posted on Updated on

Ligninolytic enzymes have potential applications in many fields and they are involved in the degradation of various xenobiotic compounds and dyes. Versatile peroxidases, a fungal enzyme, are industrially attractive and their applications have expanded to the field of bioremediation. Designing an enzyme that have higher catalytic activity, stability and fitting well with the required conditions are one of the challenges of today’s biotechnology. Versatile peroxidases are known to efficiently oxidize non-natural substrates like polycyclic aromatic hydrocarbons (PAHs). The accessibility of the PAHs to microbial cells is less. Hence by increasing the hydrophobicity of versatile peroxidases, the chance of the enzyme to meet the hydrophobic substrates such as PAHs in a contamination site can be increased. We have used an insilico approaches for optimal designing of versatile peroxidase to enhance its bioremediation ability.

http://www.scitechnol.com/homology-modeling-of-versatile-peroxidases-from-pleurotus-sapidus-reveals-residues-for-site-directed-mutagenesis-to-enhance-the-bioremediation-ability-iGg7.php?article_id=2558

A Unified Bug Testing Software for Biological and Other Systems

Posted on Updated on

Automatic bug testing is very crucial for software systems that are widely used. This is especially true when the system is very complex. Unexpected and undesired events could happen due to the presence of bugs. For instance, a web system might take a very long time on a specific query because of the presence of a bug. We cannot expect the creators of the web system to be continually monitoring the system looking for such events. It will greatly benefit the creators of the web system if such events can be automatically detected and if they are notified in a timely fashion. In this paper we report one such bug testing software that we have created for the MnM web system for motif search. MnM is widely used by biologists all over the globe. We feel that the architecture we have employed for our bug testing software is generic and can be applied to other software systems as well. There exist numerous conventional bug testing software tools which are designed to perform only functional or graphical user interface testing.

http://www.scitechnol.com/a-unified-bug-testing-software-for-biological-and-other-systems-XEt4.php?article_id=2557

A Rarely Seen Entity: Morbus Morbihan Disease

Posted on

Morbus Morbihan disease is granulomatous complication characterized with facial edema occuring due to acne or rosacea. It is resistant to treatment; diagnosis could be difficult. 48 years old male patient applied to our polyclinic with complaint of swelling on left side of his face, around his eye and cheeks, persistent for 6 months. He previously applied to dermatology, dental and Otorhinolaryngology departments in various hospitals but no diagnosis could be made. There was no trauma, exposure to sun, drug use history or symptoms like pain and itch. He was complaining about visual swelling. He had edema stretching from left side of his face to orbital area and mild erythema in his dermatological examination. Our pathology department reevaluated biopsy preparations taken by the center he previously went. Rosacea lymphedema was reported. Doxycycline, ornidazole, ketotifen and flutamide were administered by assuming that patient has Morbus Morbihan disease. In the next examination after one month, it has been observed that edema was diminished. In fourth month, edema decreased a lot. Thus treatment was stopped. The patient was applied again in the following 2 months due to increase at edema on his face. That time 0.5 mg/day isotretinoin treatment started and at third month edema regressed. We found this case appropriate to present to emphasize that it is rare and that it should be considered.

To know more: http://bit.ly/1QM6nmv
Submit your manuscript: dermatology@scitechnol.com (or) dermatology@scitechnol.org

Healthcare Demographics and Specialty Variation in Atopic Dermatitis

Posted on

Importance: Atopic dermatitis (AD) is a common chronic skin disease with significant comorbidities and a dramatic impact on quality of life. Despite this, there is little-published information about healthcare utilization patterns for adults and children with AD.
Objective: To examine healthcare utilization for patients with AD who are cared for in a regional academic medical center.
Design: Retrospective cohort analysis. Setting: A mixed urban, suburban and rural catchment in the Western NY region.
Participants: All patients seeking medical care for their AD from March of 2011 to September 2015.
Main Measure(s): Age, sex, race, ethnicity, (demographics) and medical specialty (healthcare utilization). Patients were stratified and analyzed by age group.
Results: Adult AD patients (n=767) accounted for 38.2% of the AD population seeking healthcare in our system with a mean age of 42.7 ± 18.7 years. Among adults, females were seen more commonly than males (65.3% vs. 34.7%). In contrast, both genders were equally represented in the pediatric population (18 years; 35.2%). Dermatologists cared for the majority of patients (35.2%), followed by pediatricians (25.7%) and family medicine physicians (10.1%). African-Americans were nearly 3 times more likely than Caucasians to visit primary care physicians for their initial AD management (p<0001).
Conclusions and relevance: This study demonstrates that adult AD patients account for over a third of all AD visits in a regional academic medical center. Dermatologists managed the greatest number of AD patients, and the pediatric population was notable for a greater proportion of African American patients relative to the adults. This disparity between the proportions of African Americans in pediatric vs adult patients may reflect reduced access to care for adults. Alternatively, African-Americans may simply have a greater prevalence of pediatric onset AD coupled with greater disease resolution prior to adulthood. African-Americans also appear to seek

To know more: http://bit.ly/1QM6nmv
Submit your manuscript: dermatology@scitechnol.com (or) dermatology@scitechnol.org

Ways to Treat Damaged Hair in Winter

Posted on

It’s been a rough winter for most of the country. When you’ve got arctic temperatures and gusting winds you’ve also got low humidity in the air. And low humidity not only dries out your skin but also dries out your #hair. If your hair is feeling dry and brittle and is seeking the summer warmth, then read on.

Here are four tips to help you repair your damaged winter hair:

1. Reduce shampooing. Shampooing every second or third day will allow natural oils to remain on your hair and scalp and prevent further drying.

2. Go deep. Once to twice a week, massage a deep conditioner into your hair and scalp and let it rest as you shower. Then rinse with warm water. For extremely dry hair, try using a leave-in deep conditioner or conditioning hair mask that you apply before bedtime and rinse the following morning. Be sure to wear a hair net and to place a towel on your pillow so you don’t stain your bed sheets.

3. Go natural. Using hair dyers and other heating devices take a toll on your hair. When possible, allow your hair to air-dry, but aim for at least once to twice a week.

4. Cool off. Some women who chemically treat their hair (think highlights) and use heating devices regularly (think flatirons), develop trichorrhexis nodosa, or hair breakage. Once hair is broken, you can’t fix it. You can minimize additional damage by reducing usage of heating devices. Try every second or third day instead of every day.

To know more: http://bit.ly/1QM6nmv
Submit your manuscript: dermatology@scitechnol.com (or) dermatology@scitechnol.org

Cancer Radioimmunotherapy

Posted on Updated on

Radioimmunotherapy (RIT) uses an antibody labelled with a radionuclide to deliver cytotoxic radiation to a target cell. In cancer therapy, an antibody with specificity for a tumor-associated antigen is used to deliver a lethal dose of radiation to the tumor cells. The ability for the antibody to specifically bind to a tumor-associated antigen increases the dose delivered to the tumor cells while decreasing the dose to normal tissues.

Cardio-vascular imaging

Posted on Updated on

Cardiovascular imaging including echocardiography, magnetic resonance, computed tomography, nuclear and invasive imaging. These domains include magnetic resonance imaging, computed tomography, X-ray imaging, intravascular imaging, and applications in nuclear cardiology and echocardiography, and any combination of these techniques. Clinical applications of such imaging techniques include improved diagnostic approaches, treatment, prognosis and follow-up of cardiovascular patients for better characterization of cardiovascular diseases, and assessment of the efficacy of new drugs and interventional devices.

Protect your brain as you age

Posted on Updated on

Research suggests that a few strategies can help guard against Alzheimer’s disease:

  • Believe you have control. Findings from a large national study of people in midlife suggest that those who believe they have greater control over their physical and cognitive health have better memory and intellectual functioning as they age.

    When people feel they don’t have control, they’re likely to be anxious and distressed. Those feelings can interfere with performance. They can also keep people from finding alternative strategies to help compensate for mental and physical decline.

  • Give your brain a workout. Research has found a clear connection between advanced education and good cognitive functioning. That’s because people with advanced education are more likely to find ways of working around cognitive problems.

    Didn’t get too far in school? Don’t worry. The research suggests that engaging in mentally stimulating activities like reading, going to classes or playing musical instruments can improve your cognitive functioning.

  • Exercise your body. Research in animals has found that exercise prompts new neural connections.

    Journal home page: https://www.scitechnol.com/research-and-reviews-psychology.php

Testing for Alzheimer’s

Posted on Updated on

Psychologists have identified several promising tests:

  • Paired-associate learning test. In this test, people try to remember related pairs of words and unrelated pairs.For most people, it’s easier to remember the related word pairs. But people destined to develop Alzheimer’s disease don’t do any better when the words are related than when they’re not, according to findings from the Longitudinal Aging Study (PDF, 140 KB).
  • Perceptual identification task. People undergoing this test read words aloud as they appear briefly on a computer screen. Experimenters repeat some words to test for “priming,” a sense of familiarity that should allow test-takers to read those words faster. Priming doesn’t help people at high risk of developing Alzheimer’s, the Amsterdam researchers found. That’s a sign that these individuals aren’t learning as well as they should.
  • Visual association test. In this test, people try to remember line drawings that have been illogically paired with other objects.Poor performance on this test suggests problems in episodic memory, according to the Amsterdam researchers.

    Journal home page: https://www.scitechnol.com/research-and-reviews-psychology.php

Enhance Your Memory

Posted on Updated on

Use these strategies to compensate for mild memory loss.

Psychologists are finding strategies to help people adapt to memory problems, including:

  • Take mental snapshots. Good memory is actually good learning, say rehabilitation experts. That means forming a strong association with new information as you learn it.

    Systematically take note of things. When you put down your keys, for instance, take a mental snapshot of them lying next to the fruit bowl on the kitchen table.

  • Train your brain to remember. People in the early stages of memory loss can benefit from simple memory training, research suggests.

    To learn a new name, for example, use “mnemonic devices” that link the new information with familiar information. If you meet someone named “Mr. Brown,” picture him drenched in that color as you’re introduced.

    Another training technique is one called “vanishing cues.” If you can’t remember a name, write down any letters of it that you can remember. Then fill in more and more until your recall kicks in. This training works by bypassing the faulty areas of the brain. Instead, you’re training new areas of the brain to take over.
     

    Journal home page: https://www.scitechnol.com/research-and-reviews-psychology.php

Neuronal Network and its Interconnectivity in Neuroscience

Posted on Updated on

Our brain has 100 billion neurons with trillions of synaptic connections between them which interact to form a coherent representation of the outside world. The simplest definition of a neural network, more properly referred to as an ?artificial? neural network, is provided by Dr. Robert Hecht-Nielsen. He defines a neural network as a computing system made up of a number of simple, highly interconnected processing elements, which process information by their dynamic state response to external inputs. There are many neuron wallpapers in the world of neuroscience that gives us a realistic image of the neurons and the network connectivity, but it is interesting when we see such an image in the nature. We present a photograph taken from a thorn bush in a hill near Shiraz, Iran, that at the first glance shares a striking resemblance with a neuronal network and its interconnectivity of the human brain.

Full Text link: http://www.scitechnol.com/peer-review/similarity-of-thorn-bush-with-neuronal-network-and-its-interconnectivity-inneuroscience-DaQA.php?article_id=5613

 

Journal home page: https://www.scitechnol.com/spine-neurosurgery.php

Tumor Necrosis Factor Inhibitors on Spine in Spondylarthritis

Posted on Updated on

The structural efficacy of TNF alpha in spine in spondylarthrities (SpA) has been reported in several studies with prolonged follow. None of these studies did however assessed their effects in a particulary severe population of SpA with hip disease. A comparative multicenter cohort study has included two groups of SpA patients with Group 1: Patients under TNF inhibitors and group 2: TNF alpha inhibitors naive patients under conventional treatment. Clinical, biological and radiological (using mSASSS score and BASRI spine) evaluations were performed before applying anti TNF (T0), after 2 years (T2) and after a period of treatment with n ≥3 (Tn) and compared to group 2.

 

Full Text link: http://www.scitechnol.com/peer-review/structural-effect-of-tumor-necrosis-factor-inhibitors-on-spine-in-spondylarthritis-patients-with-hip-involvement-M7SN.php?article_id=5872

 

Journal home page: https://www.scitechnol.com/spine-neurosurgery.php