skin cancer

Molecular profiling of melanoma tumors

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The more times metastasised melanoma has mutated and the patient’s immune system has been activated against a tumour — the better the chances of survival after immunotherapy. This is what emerges from a research collaboration between Lund University in Sweden and Herlev university hospital in Denmark. The findings are now published in the scientific journal Nature Communications.

In simple terms, the treatment entails first removing the patient’s own T cells from a tumour. T cells are the part of the immune system that recognises tumour cells. The patient’s cells are then cultured in the lab and subsequently injected back into the patient.

“The aim is for them to seek out and fight a tumour and the circulating tumour cells,” explains Göran Jönsson, a researcher at Lund University. He is collaborating with Herlev university hospital in Copenhagen, which is one of few hospitals in Europe currently conducting clinical trials of this form of immunotherapy.

Although the treatment outcomes are promising, only just below half of the patients respond to this immunotherapy.

“Between 10 and 20 percent of those affected by advanced melanoma can be cured with a single treatment of adoptive T cell therapy. On the other hand, the treatment is very intensive and has many side effects. It is therefore important to be able to predict which patients stand to benefit from the treatment so that we give it to the right ones,” say, Inge Marie Svane and Marco Donia, physicians at Herlev university hospital and researchers at the University of Copenhagen.

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Artificial Intelligence helps Early Diagnosis of skin cancer

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The technology employs machine-learning software to analyze images of skin lesions and provide doctors with objective data on telltale biomarkers of melanoma, which is deadly if detected too late, but highly treatable if caught early.

The AI system — trained using tens of thousands of skin images and their corresponding eumelanin and hemoglobin levels — could initially reduce the number of unnecessary biopsies, a significant health-care cost. It gives doctors objective information on lesion characteristics to help them rule out melanoma before taking more invasive action.

The technology could be available to doctors as early as next year.

E-mail us: dermatology@scitechnol.com

https://www.scitechnol.com/clinical-dermatology-research-journal.php

Get the Best Results From Beauty Products

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It is certainly not from exotic ingredients or brand-name only products. Obtaining great results depend on having a complete skin care routine. This routine should consist of skin-compatible products, targeted for your desired results. For example, if acne is your main focus, purchase products that combat acne. If lines and wrinkles are bothering you, don’t overload and complicate your product usage. Choose items that target your issues.

It’s actually that simple. Complete skin care means you ‘dot the essential I’s and cross the essential T’s’. And here’s where you start.

  • Cleanse skin to prepare it to absorb corrective actives.
  • Correct skin problems by choosing specific products designed to achieve your results.
  • Hydrate to maintain skin health.
  • Protect from damaging UV rays that lead to wrinkles and uneven skin pigment.

Ensure each step includes quality products. This is the secret to skin care that is repeatedly missed. Don’t be deceived by advertising claims enticing you to the latest and greatest! Learn why complete skin care is important.

While you’re at it, see my advice pages below. They will guide you to creating an effective routine for the results you want!

Read More: https://www.scitechnol.com/clinical-dermatology-research-journal.php

E-mail us: dermatology@scitechnol.com

Skin Cancer on the Rise

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The researchers report that, between 2000 and 2010, squamous cell carcinoma (also called cutaneous squamous cell carcinoma) diagnoses increased 263 percent, and basal cell carcinomas increased 145 percent. They compared the 2000-2010 period to two other segments of time: 1976-1984 and 1985-1992.

Women 30-49 experienced the greatest increase in basal cell carcinoma diagnoses; whereas, women 40-59 and 70-79 experienced the greatest increase in squamous cell carcinomas.

Men had an increase in squamous cell carcinomas between the first and second time period studied (1976-1984 and 1985-1992), but experienced a slight decline in the 2000-2010 period. However, for basal cell carcinomas, men over 29 showed similar increases in diagnoses in the 2000-2010 period than the two earlier periods.