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Effect of Lixisenatide in Type 2 diabetes

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Majority of the studies had demonstrated that baseline renal status will not affect efficacy outcomes in lixisenatide- vs placebo-treated patients, and that no lixisenatide dose adjustment is required for patients with T2D with mild or moderate renal impairment.

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Pharmacophore Modeling, 3D-QSAR, and Docking Study

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Phosphodiesterases 4 enzyme attracts the target for the designing of anti-inflammatory and bronchodilator agents. In many studies pharmacophore and atom based 3D-QSAR studies were carried out for pyrozolo[1,5-a]pyridine/4,4-dimethylpyrazolone analogues.

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Enhancement of Candesartan Cilexetil by Liquisolid Compacts

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Candesartan cilexetil belong to the class angiotensin-II receptor antagonist used in the treatment of hypertension. It is practically insoluble in water, belongs to a BCS class-II and its half life is 5.1 h with bioavailability of 15 – 40%. This is to investigate the use of liquisolid technique in improving the dissolution profile of candesartan cilexetil.

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Encapsulations for #Controlled Delivery

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Eucalyptus is reputedly represented in various Pharmacopeias for its variant pharmacology and depicts a wide range of photochemicals like triterpenoids, flavonoids, polyphenols, gallotannins and macrocarpals, both in its volatile and nonvolatile fractions.

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