https://www.scitechnol.com/liver-disease-transplantation.php

Cause of cancer form in the liver identified

Posted on Updated on

Researchers have identified the two genes whose mutation cause a serious cancer form found in the liver. The result sets concrete goals for future treatment of the otherwise incurable disease. Gastroenterology researchers tests on mice shown that the coupling of the two genes through a mutation causes a cancer tumour to develop in the liver. The researchers have made sure the genetic composition of the mutation in the mice is identical with the mutation found in human patients. This makes the researchers conclude that the gene mutation also leads to cancer in humans.

 

Know more @ http://www.scitechnol.com/liver-disease-transplantation.php

Advertisements

Promising new drug for Hep B tested

Posted on Updated on

New treatment has advanced toward human trials for chronic hepatitis B virus (HBV) infection, report scientists. The novel therapy by Arrowhead Pharmaceuticals uses a mechanism called RNA interference to reduce the surface antigens created by chronic HBV infections. Surface antigens (called HBsAg) are small molecules involved in virus entry into liver cells. In chronic infection, they may prevent the immune response from clearing the virus. For example, a high level of HBsAg can lead to a greater risk of long-term, chronic infection with hepatitis B and life-threatening complications like cirrhosis and liver cancer. In this setting, reducing HBsAg by RNA interference will have beneficial effects.

 

Know more @ http://www.scitechnol.com/liver-disease-transplantation.php

Universal vaccination has wiped out hepatitis B and associated liver cancer in Alaska’s young people

Posted on Updated on

Updated research shows that the universal hepatitis B vaccination program introduced for all newborn Alaskan children in the 1980s has wiped out hepatitis B infection and liver cancer cases associated with the infection. In the 1970s and 1980s, Alaska Native (AN) people residing in Alaska experienced the highest rates of acute and chronic hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC — liver cancer) in the USA. In 1981-82, a HBV vaccine demonstration project providing HBV screening and vaccination was conducted in 2 highly endemic regions of Alaska. In 1984, the program was extended to AN people statewide, and AN infants in tribal health facilities were offered 3 doses of hepatitis B vaccine starting at birth. At the same time, a vaccine catch-up program was conducted in schools statewide and also included reminders for AN adults that had tested negative for the virus.

 

Know more @ http://www.scitechnol.com/liver-disease-transplantation.php

Can an aspirin a day keep liver cancer away?

Posted on Updated on

A new study found that daily aspirin therapy was significantly associated with a reduced risk in hepatitis B related liver cancer. Hepatitis B is a viral infection that attacks the liver. HBV can be contracted through contact with an infected person’s blood or other bodily fluid, and the infection can either be acute or chronic. According to AASLD’s Guidelines for Treatment of Chronic Hepatitis B, an estimated 240 million people worldwide have chronic HBV, and the highest prevalence of the virus is in Africa and Asia. Death from HBV is commonly due to the development of cirrhosis (scaring of healthy liver tissue) or hepatocellular carcinoma (liver cancer).

 

Know more @ http://www.scitechnol.com/liver-disease-transplantation.php

Sweat May Pass on Hepatitis B in Contact Sports

Posted on Updated on

Sweat may be another way to pass on hepatitis B infection during contact sports, suggests research published ahead of print in the British Journal of Sports Medicine. Hepatitis B virus attacks the liver and can cause lifelong infection, cirrhosis (scarring) of the liver, liver cancer, liver failure and death.

Submit related article@ Scitechnol submission

Toward A Banana-based Vaccine For Hepatitis B

Posted on Updated on

Bananas have emerged as the best candidate to deliver a bite-sized vaccine for hepatitis B virus (HBV) to millions of people in developing countries, according to a recent article. Research efforts to genetically engineer plants as biofactories for the production of vaccines. They focus on transferring genes to produce HBV vaccine, noting that there already are 350 million carriers of hepatitis B worldwide, with 1 million new cases annually. An estimated 75 million -100 million of those infected individuals may die from liver cirrhosis or liver cancer.

Submit related article@ Scitechnol submission

New regulator of liver metabolism discovered

Posted on

Enzyme retinol saturase controls liver glucose handling. Researchers have identified an enzyme that has a major effect on glucose utilization in liver cells. The enzyme, retinol saturase, helps these cells adapt to variations in glucose levels. However, when glucose levels are consistently too high, retinol saturase appears to exert a damaging effect on cells.

Submit related article@ Scitechnol submission