Insulintropic Agents from Medicinal Plants

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Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from lack of insulin secretion or insulin sensitivity or both. Enhancement of insulin levels and insulin sensitivity is the primary target in the treatment of diabetes. Current treatment options, such as dietary modifications, oral hypoglycaemic drugs and insulin have limitations of their own. In view of this, several medicinal plants have been studied for anti-diabetic activity using various in vitro and in vivo methods. Therefore, researchers have been focusing research to find an effective and safe antihyperglycemic drug for clinical use from natural sources. The present review emphasizes on phytochemicals and medicinal plant extracts with insulin tropic activity to reduce hyperglycemia….to read more: http://www.scitechnol.com/insulinotropic-agents-from-medicinal-plants-49TF.php?article_id=2476

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Healing Potential of Citrullus Lanatus in Acetic Acid Induced Ulcerated Rats

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An attempt was made to evaluate healing potential of aqueous fruit pulp of Citrullus Lanatus (250 mg/kg, 500 mg/kg and 1000 mg/kg p.o.) on acetic acid induced ulcers in albino rats Wistar albino rats were divided in five groups of six animals in each, first group served as control and received vehicle only, second group served as standard and treated with carbenoloxone sodium 100mg/kg of bwtwhile group three, four and five were treated with fruit pulp aqueous fruit pulp extract of C.lanatus (CLE)at doses of 250, 500 and 1000 mg/kg BW, per os respectively, for five days after the induction of ulcer. All the three doses of CLE caused significant reduction in ulcer lesion index in comparison to vehicle treated group, thereby providing evidence for ulcer healing capacity. In addition to this, post treatment with CLE resulted in significant increase in the level of hexoses, sialic acid; enzymic antioxidants i.e. super oxide dismutase (SOD), catalase (CAT), with decrease in lipid peroxidase (LPO) levels….to read more: http://www.scitechnol.com/healing-potential-of-citrullus-lanatus-in-acetic-acid-induced-ulcerated-rats-CkaY.php?article_id=2712

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Skin Malignancies

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Skin malignancies are among the most common form of cancer. Dark-skinned individuals of African descent are far less likely than fair-skinned individuals to develop skin cancer. Significant differences in the pattern of skin malignancy have also been observed in different regions of the world. The pattern of skin cancer in sub-Saharan Africa shows a sharp contrast to that seen in Caucasians populations. Effective policies on public education and implementation of preventive and therapeutic strategies should be developed based on evidence of research in various regions and not on adapted models as risk factors vary among Caucasians in Europe, North America, and Australia compared to the darkly pigmented in Africa….to read more: https://www.scitechnol.com/clinical-experimental-oncology.php

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Liver Cancers

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It is also known as Hepatic Cancer, which starts in the liver. It is a condition that happens when normal cells in the liver become abnormal and grow out of control into cancer. The liver can be affected by primary liver cancer, which arises in the liver, or by cancer which forms in other parts of the body and then spreads to the liver. Most liver cancer is secondary or metastatic, meaning it started elsewhere in the body. The liver is made up of several different types of cells; several types of tumors can form there. Some of these are benign (noncancerous), and some are cancerous and can spread to other parts of the body (metastasize). These tumors have different causes and are treated differently. Liver cancers include Hepatocellular carcinoma (HCC, Cholangiocarcinoma…..to read more: https://www.scitechnol.com/clinical-experimental-oncology.php

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Use of Autologous Adipose- Derived Stromal Vascular Fraction to Treat Osteoarthritis of the Knee: A Feasibility and Safety Study

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Autologous adipose-derived stromal vascular fraction (SVF) was used to treat ten osteoarthritic knees of grades II or III (K-L scale) under an IRB-approved protocol in a feasibility and safety study. The primary objective of this study was to determine if adipose-derived SVF can be safely used for intra-articular injection of the knee.

SciTechnol.

Characteristics of Human Amniotic Epithelial Cells and Bone Marrow Mesenchymal Stem Cells in a Parallel Study: Hanging Drop Colony Formation and Doubling Time

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Amniotic epithelial cells exhibit pluripotent capacity with some unique properties. They are considered as a good candidate in regenerative medicine. Human bone marrow mesenchymal stromal cells (hBM-MSC) are the gold standard in cell therapyprocedures, but whether these cells could be replaced with hAEC remains a debate? We compared the stem cellcharacteristics of hAEC with hBM-MSC considering isolation, morphology, population doubling time, colony formation on substratum and in suspension, alkaline phosphatase activity and expression of some CD Markers. hAEC were round and cubical but hBM-MSC appeared spindle-shaped in culture. Both groups of cells expressed mesenchymal stem cells markers (CD44, CD90) and they did not express CD34. OCT4 was highly expressed in hAEC but not in hBM-MSC.read more

Scitechnol

Study of Isotope D/H Composition in Women Liquid Media during Lactation

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Carried studies of isotope (D/H) composition in liquid media in women during physiological lactation revealed different deuterium concentrations presence, which significantly differ in saliva, blood plasma and woman breast milk. Thus the highest deuterium concentrations observed in the saliva, which surpassed deuterium content in the blood plasma (by 99 ‰) and breast milk (by 117 ‰). Inclusion in drinking diet deuterium depleted water (-614 ‰,volume 1.5 liters per day, for 30 days) led to significant decrease of deuterium concentration in all liquid media on average by 102-160 ‰, on background it was noted some smoothing of differences between biological media with preservation of deuterium concentration decrease gradient in the same sequence as inphysiological conditions.

For more information please visit: http://www.scitechnol.com/la-prensa-medica.php

Manuscript: Submission: editor.lpma@scitechnol.org