Statistical Methods in Evaluation of Multidimensional Symptoms in Nursing Research

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Since completing advanced degrees in statistics and epidemiology, I have participated in nursing research at Yale School of Nursing (YSN) by providing statistical support for grants. While analyzing data from diverse subjects with cancer, diabetes, sleep disorders, cardiac disease, autism, and other health conditions, I have encountered common statistical problems with inter-correlated multidimensional outcomes in longitudinal observations. One of my primary research interests is to find analytic methods to overcome statistical problems in symptom evaluation.

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Premenstrual Syndrome (PMS)

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This is felt to be an exaggerated presentation of molimina, the symptoms that many women experience in the luteal phase of the cycle and which accompany ovulatory cycles. An important attribute is that symptoms are found in the luteal phase, and absent in the postmenstrual week. Although many hypotheses exist, the etiology is essentially unknown.

An eel’s glow could illuminate liver disease

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A protein in the muscles of Japanese freshwater eels glows green  when it meets the compound bilirubin, a breakdown product of red blood cells. Scientists have used a lab-made version of the protein to measure bilirubin levels in blood, a good indicator of liver function.

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Primary dysmenorrhea

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It is painful menses without evidence of an organic lesion or cause, usually brief, and worst on the first day of menstruation. This type of dysmenorrhea is seen in ovulatory menstrual cycles, usually within five years of menarche, and improves with age. Most theories center around excess prostaglandin PGF2alpha, resulting in smooth muscle contraction. The role of estrogen and progesterone is unclear: estrogen is a stimulator of uterine activity, and progesterone is an inhibitor. Yet women with high levels of estrogen, such as those with anovulatory cycles and obesity, typically do not experience much dysmenorrhea.

An Evaluation of Nurses Retention Strategies used by the Botswana Health Sector

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This study evaluates the strategies used to retain qualified nurses in the Botswana Health Sector. The purpose of this paper was to gain insight into the problem of nurse retention in the hospital setting. The goal was to find ways to empower nurses and create a better workplace. By creating a better work environment, hospitals may be able to retain more of their nurses. Retention would cut the cost of replacing nurses and assist hospitals with the ongoing nurse shortage. This paper has offered strategies that may provide guidance into reducing the turnover rate that exists among nurses in many hospitals across the country.

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Epigenetic changes caused by binge drinking: Overconsumption of alcohol triggers inflammatory response in the liver

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Researchers have identified epigenetic protein changes caused by binge drinking, a discovery that could lead to treatments for alcohol-related liver diseases. Excessive alcohol use is one of the most common causes of chronic liver failure. Long-term liver damage from alcohol use is irreversible. Excessive alcohol use is also associated with high blood pressure, heart disease, stroke, cancer and digestive problems.

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What do you know about Transfusion medicine..??

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Transfusion Medicine is a branch of medicine that deals with the transfusion of blood and its components. The study concerns about the process of transfusion chain. The study of transfusion medicine includes: Processing of Blood products, Imunohematology, Stem cell research, Cell therapy, Apheresis.

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