Insulintropic Agents from Medicinal Plants

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Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from lack of insulin secretion or insulin sensitivity or both. Enhancement of insulin levels and insulin sensitivity is the primary target in the treatment of diabetes. Current treatment options, such as dietary modifications, oral hypoglycemic drugs and insulin have limitations of their own. In view of this, several medicinal plants have been studied for anti-diabetic activity using various in vitro and in vivo methods. Therefore, researchers have been focusing research to find an effective and safe antihyperglycemic drug for clinical use from natural sources. The present review emphasizes on phytochemicals and medicinal plant extracts with insulinotropic activity to reduce hyperglycemia. This review also categorized phytochemicals and plant extracts based on their mode of action like insulin secretagogues, insulin mimetics and both…………………………..to read more: http://www.scitechnol.com/insulinotropic-agents-from-medicinal-plants-49TF.php?article_id=2476

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Atipic Axillary Mass: Follicular Dendritic Cell Sarcoma within Castleman’s Disease: A Case Report and Review of Literature

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Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm (0.4% of soft tissue sarcomas) originating from follicular dendritic cells. On the other hand, Castleman’s disease (CD) is a rare lymphoproliferative disorder first described in 1956 by Castleman et al as a benign, localized enlargement of hyperplastic lymph nodes. Castleman´s disease has been found in association with FDCS in a minority of cases, suggesting that it may represent a precursor lesion. Combination of both FDCS and unicentric CD is extremely rare.As far as we know, there are no documented cases of a follicular dendritic cell sarcoma within a hyaline-vascular Castleman´s disease localized in the axilla.There is no consensus about treatment strategy in this situation; surgical resection when possible seems to be the best option, with or without complementary radiotherapy……………………………………………to read more at: http://www.scitechnol.com/atipic-axillary-mass-follicular-dendritic-cell-sarcoma-within-castlemans-disease-a-case-report-and-review-of-literature-csh2.php?article_id=3446

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A diagnostic biomarker: differential expression of LMP2/β1i in human uterine neoplasms

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Uterine leiomyosarcoma (Ut-LMS) more frequently develops in the muscle tissue layer of the uterine body than in the uterine cervix. The development of gynecological tumors is often correlated with the secretion of female hormones; however, the development of Ut-LMS has not been correlated with hormonal conditions, and risk factors remain unknown. A diagnostic biomarker that can distinguish malignant Ut-LMS from benign tumor leiomyoma (LMA) has not yet been established. Therefore, an analysis of the risk factors associated with human Ut-LMS is needed in order to establish a treatment method. Proteasome LMP2/β1i-deficient mice spontaneously develop Ut-LMS, with a disease prevalence of ~40% by 14 months of age…..to read more: http://www.scitechnol.com/a-diagnostic-biomarker-differential-expression-of-lmpi-in-human-uterine-neoplasms-10.41722324-9110.1000128.php?article_id=2217

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Study compares arm measures to body mass index for assessing leukaemia survivor’s nutritional status

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A simple method named is to figure out if a person is overweight or obese, and because it can distinguish between fat and muscle mass, unlike body mass index (BMI). Arm anthropometry is a valuable method for assessing muscle loss in long-term survivors of childhood cancer.

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Potential Mechanism of SGLT2i Induced Euglycaemic Diabetic Ketoacidosis

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Sodium glucose co-transporter 2 inhibitors are a new group of drugs available to treat patients with type 2 diabetes mellitus. Recently, FDA has sounded a warning of higher risk of Diabetes ketoacidosis among patients treated with this group of agents. This article reviews the available evidence to build a potential hypothesis to explain the development of this complication.to read more…http://www.scitechnol.com/abstract.php?abstract_id=3646

Comparison of Hypertension and Obesity Parameters in Healthy Adolescents and those with Polycystic Ovarian Syndrome

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The prevalence of hypertension and obesity among the adolescents with Polycystic Ovarian Syndrome (PCOS) in Shiraz is a crosssectional, descriptive study was conducted on 3200 high-school students in 2010. 146 adolescents were diagnosed with PCOS by an endocrinologist. Besides, 46 healthy adolescents were selected as the control group. Comparison of the prevalence of obesity to read more..http://www.scitechnol.com/abstract.php?abstract_id=3778

Minimally Invasive Cardiac Surgery

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Heart surgery traditionally involves an invasive procedure and the heart is stopped so that surgeons can make the necessary repairsMinimally invasive techniques are being studied to treat a number of heart conditions for certain high-risk patients that previously have been treated only by open heart surgerySmaller incisions mean shorter hospital stays and less recovery time. New techniques include replacing heart valves percutaneously and repairing aortic dissections (tears) and aneurysms with endovascular stent grafts.

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