Time-Dependence of Beat-to-Beat Muscle Blood Flow between Isometric Contraction and Relaxation

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Blood flow (BF) due to muscle contractions during exercise providing information about increased oxygen supply and energy metabolism, which may be the underlying mechanism of exercise therapy for cardiovascular disease. The same mechanism also normalizes the central and peripheral hemodynamics in body. High time resolution Doppler ultrasound measurements have been reported to detect not only the beat-to-beat blood velocity profile in the nonmuscular contraction state (basal resting condition), but also alterations in blood velocity profile in exercising limb during muscle contractions. During sustained isometric (static) muscle contraction (IMC), the systole-diastolic blood velocity profile is not intermittently disturbed due to the absence of fluctuations of intramuscular pressures compared to isotonic (dynamic) muscle contractions.

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