Role of Oxidative Stress in Male Fertility and Idiopathic Infertility: Causes and Treatment

Posted on

Epidemiological studies regarding male infertility have revealed that more and more infertile men suffer from acute or chronic inflammation of the genitourinary tract, which often occurs without any symptoms. The exact mechanism for unexplained male infertility and its correlation to oxidative stress incidence and/ or the inflammatory reactions within the male genital tract is still controversially unclear till know. Previous studies have shown the presence of cytokines such as tumor necrosis factor-α (TNF-α), a key player in the inflammation process, in the semen of infertile men. However, the mechanism of their effect on human sperm functions is still in need for further under investigations. We expect that, seminal inflammatory cytokine (TNF-α) and its expression regulator, testicular ADAM 17, will be varied, when seminal OS is established, that in turn, will vary cellular integrity and energy status. As conventional treatment of male infertility such as mineral and vitamins supplementation has poor success rates and leaves a lot to be desired, natural antioxidant ingredients are greatly suggested, nowadays, to ameliorate oxidative stress and the inflammatory detrimental effects accompanied to idiopathic male infertility.

Read more at https://www.scitechnol.com/role-of-oxidative-stress-in-male-fertility-and-idiopathic-infertility-causes-and-treatment-Y5e5.php?article_id=2524

Visit Journal at https://www.scitechnol.com/diagnostic-techniques-biomedical-analysis.php

Submit manuscript at editor.jdtba@scitechnol.com

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s