Polycystic ovary syndrome (PCOS) is a complex condition that affects approximately 5% of women. PCOS are lack of ovulation resulting in irregular periods, few or no periods, infertility, and ovaries with multiple cysts. Insulin resistance is the most common features of polycystic ovary syndrome, and studies suggest that vitamin D deficiency may have role in insulin resistance. Research suggests vitamin D may play an important role in reproductive health. Due to the presence of vitamin D receptors throughout the ovaries and endometrium, researchers theorize that vitamin D may act locally to regulate the function of these organs. Recent study show that there was a beneficial effect of vitamin D supplementation on ovulatory dysfunctions and blood pressure. Post-supplementation, there were decrease in insulin resistance and increase in insulin sensitivity. A better improvement was gained in regulating menstrual abnormalities, follicle maturation and infertility. Researchers recently conducted a meta-analysis of RCTs to determine whether vitamin D supplementation may provide a treatment effect among women with PCOS.
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