Mice that lost sense of smell stayed slim on high fat diet, while littermates ballooned in weight. Researchers developed ways to temporarily eliminate the sense of smell in adult mice, and discovered that those mice that lost smell could eat a high-fat diet and stay a normal weight, while littermates that retained the sense of smell ballooned to twice normal weight. Supersmellers gained more weight than did normal mice on the same high-fat diet. Smell-deficient mice burned excess fat instead of storing it, suggesting a link between smell and metabolism.
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