Clinicopathological Correlation in Dry Eye Disease

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To establish the strength of the association between routine tear function tests and conjunctival impression cytology (CIC) and to determine whether they simulate the morphological and cytological changes that occur on the ocular surface in dry eye.

Fifty six patients (30 cases and 26 controls) were included in the study. The tear film profile included tear film break up time (TBUT), Schirmer’s-1, Rose Bengal scores (RBS), and impression cytology. CIC samples were obtained from the infero-temporal quadrant of bulbar conjunctiva and stained with Papanicolaou stain (PAP) and Periodic Acid Schiff (PAS) stains.

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