Sample Collection Procedures and Impact on QuantiFERON®-Gold in Tube Results

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Accurate diagnosis of infection with Mycobacterium tuberculosis is important in low prevalence populations, such as healthcare workers, subjected to serial- or mass entry screen testing. There is no gold standard laboratory test for detecting latent tuberculosis infections (LTBI). Interferon-γ (IFN-γ) release assays (IGRAs) are in vitro immunodiagnostic tests that measure the effecter T cell– mediated IFN-γ response to synthetic Mycobacterium tuberculosis– specific polypeptides. When compared to the tuberculosis skin test (TST) IGRAS, including the QuantiFERON-TB Gold In-Tube (QFTGIT, QIAGEN GmbH, GER), have been shown to reduce the number of false positive LTBI diagnoses and thus substantially lower followup costs.

Read more at https://www.scitechnol.com/peer-review/sample-collection-procedures-and-impact-on-quantiferongold-in-tube-results-zcfa.php?article_id=3696

Visit Journal at https://www.scitechnol.com/diagnostic-techniques-biomedical-analysis.php

Submit manuscript at editor.jdtba@scitechnol.com

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