Trauma-specific Grey Matter Alterations in PTSD

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A quantitative voxel-wise meta-analysis of GM changes in PTSD by different traumas using AES-SDM, and found that GMR regions were generally located in the prefrontal-limbic-striatal system. Notably, subgroup analyses revealed that the GMR patterns were associated with specific trauma categories. This study provides further evidences of different neural correlates underlying PTSD by different traumas, and suggests that stratified diagnosis and treatment of PTSD are necessary in clinics.

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