Treatment of Solitary Plasmacytoma of the Axial Spine and Dorsal Spine

Posted on

Solitary plasmacytoma of the spine accounts for 5% of plasmacytomas and is a rare entity . More than 25- 60% of these lesions are localized in the dorsal spine and cause myelopathy in 42-71% of the patients. Diagnosis and treatment protocols have been established, however the final decision of whether to stabilize and irradiate locally versus direct irradiation is controversial. Many centers advocate different treatment protocols based on their institutional experience and patient outcomes.

In the presence of solitary spinal lesions, despite the location, solitary plasmacytoma of the bone should be considered as one of the differential diagnosis. Abnormal proteinemia or proteinuria may often be absent, yet this entity is commonly encountered in clinical practice. Patients show clinical and neurological improvement with surgical decompression with/ without stabilization. Postoperatively, radiotherapy is advocated since it reduces the recurrence rates. Often confused with spinal tuberculosis, starting ATT can be detrimental to the patient since it delays the standard line of treatment.

Full text:



Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s