Clinical Grading Scales for Predicting Early Neurological Worsening in Spontaneous Intracerebral Hemorrhage

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Introduction: Early neurological worsening (ENW) is a major determinant of death in spontaneous intracerebral hemorrhage. In recent years, several clinical grading scales have been developed to identify patients at risk of 30-day or 90-day poor outcome following spontaneous (ICH), but whether these are able to predict ENW remains unclear. The aim of our study was to validate and compare two ICH grading scales for predicting ENW.

 Methods: Original (o) ICH and FUNC scores were calculated for 128 consecutive, prospectively-collected ICH patients using components and cutoff values identical to those described in the original derivation cohorts. Receiver operating characteristic (ROC) analysis, including area under the curve (AUC), was used to assess the ability of each score to predict ENW.

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