Enhancement of Candesartan Cilexetil by Liquisolid Compacts

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Candesartan cilexetil belong to the class angiotensin-II receptor antagonist used in the treatment of hypertension. It is practically insoluble in water, belongs to a BCS class-II and its half life is 5.1 h with bioavailability of 15 – 40%. This is to investigate the use of liquisolid technique in improving the dissolution profile of candesartan cilexetil.

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