Aptamers- Future therapeutics

Posted on Updated on

Aptamers are oligonucleotides derived from an in-vitro evolution process called SELEX (Systematic Evolution of Ligands by Exponential Enrichment). The oligonucleotides sequences that have the tendency to bind to a wide range of target molecules, such as drugs, proteins or other organic or inorganic molecules with high affinity and specificity. Now, with the development of SELEX process, the isolation of small oligonucleotides that possess the capacity to recognize various classes of target molecules have been made much easier. Aptamers have been evolved to bind proteins which are associated with a number of disease states. These molecules offer a strong potential compare to the antibody classes in terms of therapeutic and diagnostic applications. Aptamers exhibit significant advantages relative to protein therapeutics in terms of size, synthetic accessibility and modification the contempery need for treatment of aquaculture diseases. With the increasing use of aptamers in numerous diagnostics, therapeutics and other such aspects, it is likely that the perception of nucleic acid therapeutics will be changed and that aptamers may form the basis of future therapeutics.

Know about aptamers and it’s future perspectives @ http://www.scitechnol.com/peer-review/aptamers-a-novel-for-respectivediagnostics-and-therapeutic-toolin-fisheries-and-aquaculture-8SAg.php?article_id=5086 @ Journal of Immunological Techniques & Infectious Diseases

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s