Striking differences were found in the volume of white matter in the brains – overweight people had bigger widespread reduction in white matter. White matter is the brain tissue that connects areas of the brain and allows information to flow between regions. Human brains begin to shrink at about middle age, but because of the recent findings investigators now believe that obesity may speed the onset and progression of brain aging. The team then calculated how white matter volume was related to age .
across the two groups. In one example, an overweight 50 year-old had a comparable white matter volume to a lean 60 year-old, implying an average difference in brain age of up to a decade.
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