Can Medulloblastoma be presented with Primary Diffuse Leptomeningeal Gliomatosis? Case Report and Literature Review

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Primary diffuse leptomeningeal Gliomatosis (PDLG) is a rare neoplastic condition characterized by primary infiltration of leptomeninges by malignant glial cells which is extremely rare to be as a result of medulloblastoma. To the best of our knowledge, there are only 5 reported localized forms of PDLG cases due to medulloblastoma affecting mainly posterior fossa and/or part of cerebrum. In this article, we are reporting for the first time a case of PDLG with extensive diffuse involvement of leptomeninges due to medulloblastoma extending from the cerebrum to sacral area in 4-year old child presented with acute headache, abducent nerve palsy and papilledema with dramatic response to chemotherapy….to read more: http://www.scitechnol.com/peer-review/can-medulloblastoma-be-presented-with-primary-diffuse-leptomeningeal-gliomatosis-case-report-and-literature-review-rxW4.php?article_id=5746

Contact us by E-mail: editor.jceog@scitechnol.com and cancers@clinicalmedicaljournals.com

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